Cycloastragenol manufacturers

Cycloastragenol is a high-value triterpenoid saponin derived from Astragalus membranaceus. B2B buyers should prioritize purity levels of 98% or higher (determined by HPLC) for pharmaceutical or high-end nutraceutical applications. Ensure the product is a fine white crystalline powder and verify the CAS number (78574-94-0) to avoid confusion with Astragaloside IV. High-quality batches must have a low moisture content (<2.0%) and a heavy metal profile that meets international safety limits (e.g., Lead <0.5ppm, Arsenic <0.5ppm).

Due to its use in health supplements, suppliers must provide a comprehensive Certificate of Analysis (COA) for every batch. For entry into regulated markets like the US or EU, look for suppliers with GMP (Good Manufacturing Practice) certification and ISO 22000 or HACCP for food safety management. If the product is intended for the US market, ensure the supplier can provide documentation supporting NDI (New Dietary Ingredient) status or GRAS (Generally Recognized as Safe) self-affirmation where applicable.

Cycloastragenol is sensitive to environmental factors. It must be stored in cool, dry conditions, ideally at 2-8°C for long-term stability, and kept away from strong light and heat. Buyers should ensure the supplier uses vacuum-sealed aluminum foil bags or high-density polyethylene (HDPE) drums with double-layer food-grade plastic liners to prevent oxidation and moisture absorption during transit.

Cycloastragenol is primarily sought after for its telomerase activation properties, making it a cornerstone ingredient in anti-aging supplements and longevity research. It is also used in cosmeceuticals for skin rejuvenation and in immunomodulatory formulas. Buyers should confirm the solubility profile (typically soluble in ethanol or DMSO) to ensure compatibility with their specific end-product formulation (capsules, creams, or tinctures).

The high cost of Cycloastragenol makes it a target for adulteration. Always request a pre-shipment sample for independent third-party testing (e.g., SGS or Eurofins). Use the Made-in-China.com Secured Trading Service to ensure that payment is only released once the quality is verified. Avoid deals that are significantly below the market price (typically $X,XXX per kg), as this often indicates sub-standard purity or synthetic substitutes.

Focus on long-term supply stability rather than just the lowest price. Negotiate a tiered pricing structure based on annual volume commitments. Ask for transparency in the extraction process—suppliers who control their own Astragalus cultivation bases offer better traceability and price stability. Request a Quality Agreement that specifies the exact testing methods (HPLC-ELSD is preferred for saponins) to be used for batch acceptance.

For Cycloastragenol, Air Freight (Express) via carriers like FedEx or DHL is recommended to minimize time in uncontrolled environments. Ensure the shipment includes a Material Safety Data Sheet (MSDS) and a Non-Hazardous Chemical Declaration to prevent customs delays. For large orders, consider temperature-controlled packaging and always insist on full-value cargo insurance to protect against loss or damage during cross-border transit.

Verify the HS Code (typically 293299 or 130219) with your local customs broker to determine the correct import duties and taxes. Be aware of CITES regulations or local restrictions on plant-derived extracts. Ensure all labels are in English and include the Batch Number, Manufacture Date, and Expiry Date to facilitate smooth customs clearance in the destination country.